Rac regulation of transformation, gene expression, and actin organization by multiple, PAK-independent pathways.

Rac1 and RhoA are members of the Rho family of Ras-related proteins and function as regulators of actin cytoskeletal organization, gene expression, and cell cycle progression. Constitutive activation of Rac1 and RhoA causes tumorigenic transformation of NIH 3T3 cells, and their functions may be requ...

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Hlavní autoři: Westwick, J K, Lambert, Q T, Clark, G J, Symons, M, Van Aelst, L, Pestell, R G, Der, C J
Médium: Artigo
Jazyk:Inglês
Vydáno: 1997
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC231857/
https://ncbi.nlm.nih.gov/pubmed/9032259
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