Rac regulation of transformation, gene expression, and actin organization by multiple, PAK-independent pathways.

Rac1 and RhoA are members of the Rho family of Ras-related proteins and function as regulators of actin cytoskeletal organization, gene expression, and cell cycle progression. Constitutive activation of Rac1 and RhoA causes tumorigenic transformation of NIH 3T3 cells, and their functions may be requ...

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Библиографические подробности
Главные авторы: Westwick, J K, Lambert, Q T, Clark, G J, Symons, M, Van Aelst, L, Pestell, R G, Der, C J
Формат: Artigo
Язык:Inglês
Опубликовано: 1997
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC231857/
https://ncbi.nlm.nih.gov/pubmed/9032259
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