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Pak1 and Pak2 are activated in recurrent respiratory papillomas, contributing to one pathway of Rac1-mediated COX-2 expression

Recurrent respiratory papillomas are pre-malignant tumors of the airway caused by human papillomaviruses (HPVs), primarily types 6 and 11. We had reported that respiratory papillomas overexpress the epidermal growth factor receptor (EGFR), the small GTPase Rac1 and cyclooxygenase-2 (COX-2), and have...

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Autors principals: Wu, Rong, Abramson, Allan L., Symons, Marc H., Steinberg, Bettie M.
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2932774/
https://ncbi.nlm.nih.gov/pubmed/20131316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.25226
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