Induction of senescence-like phenotypes by forced expression of hic-5, which encodes a novel LIM motif protein, in immortalized human fibroblasts.

The hic-5 gene encodes a novel protein with Zn finger-like (LIM) motifs, the expression of which increases during cellular senescence. The ectopic expression of hic-5 in nontumorigenic immortalized human fibroblasts, whose expression levels of hic-5 were significantly reduced in comparison with thos...

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Hlavní autoři: Shibanuma, M, Mochizuki, E, Maniwa, R, Mashimo, J, Nishiya, N, Imai, S, Takano, T, Oshimura, M, Nose, K
Médium: Artigo
Jazyk:Inglês
Vydáno: 1997
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC231847/
https://ncbi.nlm.nih.gov/pubmed/9032249
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