Role of diacylglycerol-regulated protein kinase C isotypes in growth factor activation of the Raf-1 protein kinase.

The Raf protein kinases function downstream of Ras guanine nucleotide-binding proteins to transduce intracellular signals from growth factor receptors. Interaction with Ras recruits Raf to the plasma membrane, but the subsequent mechanism of Raf activation has not been established. Previous studies...

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Main Authors: Cai, H, Smola, U, Wixler, V, Eisenmann-Tappe, I, Diaz-Meco, M T, Moscat, J, Rapp, U, Cooper, G M
Formato: Artigo
Idioma:Inglês
Publicado: 1997
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC231799/
https://ncbi.nlm.nih.gov/pubmed/9001227
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