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The murine C'-terminally alternatively spliced form of p53 induces attenuated apoptosis in myeloid cells.

The onset of p53-dependent apoptosis results from the accumulation of damaged DNA. Recently, it was shown that the C' terminus of the p53 protein plays a central role in sensing damaged DNA. In our present study, we examined the role of the C' terminus in the induction of apoptosis. A temp...

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Autors principals: Almog, N, Li, R, Peled, A, Schwartz, D, Wolkowicz, R, Goldfinger, N, Pei, H, Rotter, V
Format: Artigo
Idioma:Inglês
Publicat: 1997
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC231797/
https://ncbi.nlm.nih.gov/pubmed/9001225
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