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The murine C'-terminally alternatively spliced form of p53 induces attenuated apoptosis in myeloid cells.

The onset of p53-dependent apoptosis results from the accumulation of damaged DNA. Recently, it was shown that the C' terminus of the p53 protein plays a central role in sensing damaged DNA. In our present study, we examined the role of the C' terminus in the induction of apoptosis. A temperature-se...

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Udgivet i:Mol Cell Biol
Principais autores: Almog, N, Li, R, Peled, A, Schwartz, D, Wolkowicz, R, Goldfinger, N, Pei, H, Rotter, V
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 1997
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231797/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9001225/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.17.2.713
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