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Modeling how many envelope-glycoprotein trimers per virion participate in human immunodeficiency virus infectivity and its neutralization by antibody
Trimers of the HIV-1 envelope glycoprotein (Env) effectuate viral entry into susceptible cells. Therefore Env trimers are the targets for neutralizing antibodies. This study models the number of trimers required for virion infectivity. It also delineates the minimum number of antibody molecules that...
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| Hovedforfatter: | |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2007
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2317823/ https://ncbi.nlm.nih.gov/pubmed/17825343 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2007.06.044 |
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