Histone acetyltransferase activity is conserved between yeast and human GCN5 and is required for complementation of growth and transcriptional activation.

Yeast and human ADA2 and GCN5 (y- and hADA2 and y- and hGCN5, respectively) have been shown to potentiate transcription in vivo and may function as adaptors to bridge physical interactions between DNA-bound activators and the basal transcriptional machinery. Recently it was shown that yGCN5 is a his...

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Pubblicato in:	Mol Cell Biol
Autori principali:	Wang, L, Mizzen, C, Ying, C, Candau, R, Barlev, N, Brownell, J, Allis, C D, Berger, S L
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Taylor & Francis 1997
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231776/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8972232/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.17.1.519
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