Histone acetyltransferase activity is conserved between yeast and human GCN5 and is required for complementation of growth and transcriptional activation.

Yeast and human ADA2 and GCN5 (y- and hADA2 and y- and hGCN5, respectively) have been shown to potentiate transcription in vivo and may function as adaptors to bridge physical interactions between DNA-bound activators and the basal transcriptional machinery. Recently it was shown that yGCN5 is a his...

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Dettagli Bibliografici
Autori principali: Wang, L, Mizzen, C, Ying, C, Candau, R, Barlev, N, Brownell, J, Allis, C D, Berger, S L
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1997
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC231776/
https://ncbi.nlm.nih.gov/pubmed/8972232
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