Overexpression of HOXA10 in murine hematopoietic cells perturbs both myeloid and lymphoid differentiation and leads to acute myeloid leukemia.

Multiple members of the A, B, and C clusters of Hox genes are expressed in hematopoietic cells. Several of these Hox genes have been found to display distinctive expression patterns, with genes located at the 3' side of the clusters being expressed at their highest levels in the most primitive subpo...

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Pubblicato in:	Mol Cell Biol
Autori principali:	Thorsteinsdottir, U, Sauvageau, G, Hough, M R, Dragowska, W, Lansdorp, P M, Lawrence, H J, Largman, C, Humphries, R K
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Taylor & Francis 1997
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231774/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8972230/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.17.1.495
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