Overexpression of HOXA10 in murine hematopoietic cells perturbs both myeloid and lymphoid differentiation and leads to acute myeloid leukemia.

Multiple members of the A, B, and C clusters of Hox genes are expressed in hematopoietic cells. Several of these Hox genes have been found to display distinctive expression patterns, with genes located at the 3' side of the clusters being expressed at their highest levels in the most primitive subpo...

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Publicat a:	Mol Cell Biol
Autors principals:	Thorsteinsdottir, U, Sauvageau, G, Hough, M R, Dragowska, W, Lansdorp, P M, Lawrence, H J, Largman, C, Humphries, R K
Format:	Artigo
Idioma:	Inglês
Publicat:	Taylor & Francis 1997
Matèries:	Research Article
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231774/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8972230/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.17.1.495
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