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Identification of domains of the insulin-like growth factor I receptor that are required for protection from apoptosis.

Using a series of insulin-like growth factor I (IGF-I) receptor mutants, we have attempted to define domains required for transmitting the antiapoptotic signal from the receptor and to compare these domains with those required for mitogenesis or transformation. In FL5.12 cells transfected with wild-...

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Udgivet i:Mol Cell Biol
Principais autores: O'Connor, R, Kauffmann-Zeh, A, Liu, Y, Lehar, S, Evan, G I, Baserga, R, Blättler, W A
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 1997
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231767/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8972223/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.17.1.427
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