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Active mammalian replication origins are associated with a high-density cluster of mCpG dinucleotides.

ori-beta is a well-characterized origin of bidirectional replication (OBR) located approximately 17 kb downstream of the dihydrofolate reductase gene in hamster cell chromosomes. The approximately 2-kb region of ori-beta that exhibits greatest replication initiation activity also contains 12 potenti...

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Détails bibliographiques
Auteurs principaux: Rein, T, Zorbas, H, DePamphilis, M L
Format: Artigo
Langue:Inglês
Publié: 1997
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC231766/
https://ncbi.nlm.nih.gov/pubmed/8972222
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