Ubiquitination of p53 and p21 is differentially affected by ionizing and UV radiation.
Levels of the tumor suppressor protein p53 are normally quite low due in part to its short half-life. p53 levels increase in cells exposed to DNA-damaging agents, such as radiation, and this increase is thought to be responsible for the radiation-induced G1 cell cycle arrest or delay. The mechanisms...
Guardat en:
| Publicat a: | Mol Cell Biol |
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| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Taylor & Francis
1997
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231760/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8972216/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.17.1.355 |
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