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Recombination induced by triple-helix-targeted DNA damage in mammalian cells.

Gene therapy has been hindered by the low frequency of homologous recombination in mammalian cells. To stimulate recombination, we investigated the use of triple-helix-forming oligonucleotides (TFOs) to target DNA damage to a selected site within cells. By treating cells with TFOs linked to psoralen...

詳細記述

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書誌詳細
主要な著者: Faruqi, A F, Seidman, M M, Segal, D J, Carroll, D, Glazer, P M
フォーマット: Artigo
言語:Inglês
出版事項: 1996
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC231685/
https://ncbi.nlm.nih.gov/pubmed/8943337
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