Recombination induced by triple-helix-targeted DNA damage in mammalian cells.
Gene therapy has been hindered by the low frequency of homologous recombination in mammalian cells. To stimulate recombination, we investigated the use of triple-helix-forming oligonucleotides (TFOs) to target DNA damage to a selected site within cells. By treating cells with TFOs linked to psoralen...
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| Vydáno v: | Mol Cell Biol |
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| Hlavní autoři: | , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Taylor & Francis
1996
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231685/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8943337/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.16.12.6820 |
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