Recombination induced by triple-helix-targeted DNA damage in mammalian cells.

Gene therapy has been hindered by the low frequency of homologous recombination in mammalian cells. To stimulate recombination, we investigated the use of triple-helix-forming oligonucleotides (TFOs) to target DNA damage to a selected site within cells. By treating cells with TFOs linked to psoralen...

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Pubblicato in:	Mol Cell Biol
Autori principali:	Faruqi, A F, Seidman, M M, Segal, D J, Carroll, D, Glazer, P M
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Taylor & Francis 1996
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231685/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8943337/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.16.12.6820
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