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Cdc53p acts in concert with Cdc4p and Cdc34p to control the G1-to-S-phase transition and identifies a conserved family of proteins.

Regulation of cell cycle progression occurs in part through the targeted degradation of both activating and inhibitory subunits of the cyclin-dependent kinases. During G1, CDC4, encoding a WD-40 repeat protein, and CDC34, encoding a ubiquitin-conjugating enzyme, are involved in the destruction of th...

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Detalhes bibliográficos
Main Authors: Mathias, N, Johnson, S L, Winey, M, Adams, A E, Goetsch, L, Pringle, J R, Byers, B, Goebl, M G
Formato: Artigo
Idioma:Inglês
Publicado em: 1996
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC231665/
https://ncbi.nlm.nih.gov/pubmed/8943317
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