Orientation dependence of trinucleotide CAG repeat instability in Saccharomyces cerevisiae.

To examine the chromosomal stability of repetitions of the trinucleotide CAG, we have cloned CAG repeat tracts onto the 3' end of the Saccharomyces cerevisiae ADE2 gene and placed the appended gene into the ARO2 locus of chromosome VII. Examination of chromosomal DNA from sibling colonies arisi...

詳細記述

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書誌詳細
主要な著者: Maurer, D J, O'Callaghan, B L, Livingston, D M
フォーマット: Artigo
言語:Inglês
出版事項: 1996
主題:
Research Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC231663/
https://ncbi.nlm.nih.gov/pubmed/8943315
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