Binding of human immunodeficiency virus type 1 to CD4 induces association of Lck and Raf-1 and activates Raf-1 by a Ras-independent pathway.

We have analyzed CD4-mediated signaling during the early stages of human immunodeficiency virus type 1 (HIV-1) infection. Binding of purified HIV-1 virions or recombinant HIV-1 glycoprotein gp120 to CD4 receptors resulted in association and tyrosine phosphorylation and activation of tyrosine kinase...

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Publikašuvnnas:	Mol Cell Biol
Váldodahkkit:	Popik, W, Pitha, P M
Materiálatiipa:	Artigo
Giella:	Inglês
Almmustuhtton:	Taylor & Francis 1996
Fáttát:	Research Article
Liŋkkat:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231655/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8887682/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.16.11.6532
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