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Human Immunodeficiency Virus Type 1 Uses Lipid Raft-Colocalized CD4 and Chemokine Receptors for Productive Entry into CD4(+) T Cells

In this report, we describe a crucial role of lipid raft-colocalized receptors in the entry of human immunodeficiency virus type 1 (HIV-1) into CD4(+) T cells. We show that biochemically isolated detergent-resistant fractions have characteristics of lipid rafts. Lipid raft integrity was required for...

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Bibliografske podrobnosti
Main Authors: Popik, Waldemar, Alce, Timothy M., Au, Wei-Chun
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2002
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC136131/
https://ncbi.nlm.nih.gov/pubmed/11967288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.10.4709-4722.2002
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