The Gfi-1 proto-oncoprotein contains a novel transcriptional repressor domain, SNAG, and inhibits G1 arrest induced by interleukin-2 withdrawal.

The Gfi-1 proto-oncogene is activated by provirus insertion in T-cell lymphoma lines selected for interleukin-2 (IL-2) independence in culture and in primary retrovirus-induced thymomas and encodes a nuclear, sequence-specific DNA-binding protein. Here we show that Gfi-1 is a position- and orientati...

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Publicado no:	Mol Cell Biol
Principais autores:	Grimes, H L, Chan, T O, Zweidler-McKay, P A, Tong, B, Tsichlis, P N
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 1996
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231629/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8887656/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.16.11.6263
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