Signal-induced degradation of I(kappa)B(alpha): association with NF-kappaB and the PEST sequence in I(kappa)B(alpha) are not required.

Míreanna Comhchosúla

• I kappaB alpha-independent downregulation of NF-kappaB activity by glucocorticoid receptor.
  le: Heck, S, et al.
  Foilsithe: (1997)
• Synergistic activation of NF-kappaB by tumor necrosis factor alpha and gamma interferon via enhanced I kappaB alpha degradation and de novo I kappaBbeta degradation.
  le: Cheshire, J L, et al.
  Foilsithe: (1997)
• Different mechanisms control signal-induced degradation and basal turnover of the NF-kappaB inhibitor IkappaB alpha in vivo.
  le: Krappmann, D, et al.
  Foilsithe: (1996)
• Tumor necrosis factor alpha-induced phosphorylation of I kappa B alpha is a signal for its degradation but not dissociation from NF-kappa B.
  le: Miyamoto, S, et al.
  Foilsithe: (1994)
• Activation of NF-kappa B requires proteolysis of the inhibitor I kappa B-alpha: signal-induced phosphorylation of I kappa B-alpha alone does not release active NF-kappa B.
  le: Lin, Y C, et al.
  Foilsithe: (1995)