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Specificity of Receptor – Ligand Interactions and Their Effect on Dimerisation as Observed by Electrospray Mass Spectrometry: Bile Acids Form Stable Adducts to the RXRα
Electrospray (ES) mass spectrometry data is presented showing that agonist binding to the nuclear receptor (NR), retinoid X receptor α (RXRα), is competitive. The competitive nature of agonist binding can be used to discriminate between the specific and non-specific binding of small lipophilic molec...
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| Principais autores: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2315782/ https://ncbi.nlm.nih.gov/pubmed/16258897 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jms.925 |
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