Synergistic interaction of the Neu proto-oncogene product and transforming growth factor alpha in the mammary epithelium of transgenic mice.

Transgenic mice expressing either the neu proto-oncogene or transforming growth factor (TGF-alpha) in the mammary epithelium develop spontaneous focal mammary tumors that occur after a long latency. Since the epidermal growth factor receptor (EGFR) and Neu are capable of forming heterodimers that ar...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Muller, W J, Arteaga, C L, Muthuswamy, S K, Siegel, P M, Webster, M A, Cardiff, R D, Meise, K S, Li, F, Halter, S A, Coffey, R J
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 1996
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231573/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8816486/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.16.10.5726
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