Attenuated sensitivity to neuroactive steroids in γ-aminobutyrate type A receptor delta subunit knockout mice
γ-Aminobutyric acid (GABA) type A receptors mediate fast inhibitory synaptic transmission and have been implicated in responses to sedative/hypnotic agents (including neuroactive steroids), anxiety, and learning and memory. Using gene targeting technology, we generated a strain of mice deficient in...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
1999
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC23157/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10536021/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.22.12905 |
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