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Aurora B kinase and protein phosphatase 1 have opposing roles in modulating kinetochore assembly

The outer kinetochore binds microtubules to control chromosome movement. Outer kinetochore assembly is restricted to mitosis, whereas the inner kinetochore remains tethered to centromeres throughout the cell cycle. The cues that regulate this transient assembly are unknown. We find that inhibition o...

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Autors principals: Emanuele, Michael J., Lan, Weijie, Jwa, Miri, Miller, Stephanie A., Chan, Clarence S.M., Stukenberg, P. Todd
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2315672/
https://ncbi.nlm.nih.gov/pubmed/18426974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200710019
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