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Altering the coenzyme preference of xylose reductase to favor utilization of NADH enhances ethanol yield from xylose in a metabolically engineered strain of Saccharomyces cerevisiae

BACKGROUND: Metabolic engineering of Saccharomyces cerevisiae for xylose fermentation into fuel ethanol has oftentimes relied on insertion of a heterologous pathway that consists of xylose reductase (XR) and xylitol dehydrogenase (XDH) and brings about isomerization of xylose into xylulose via xylit...

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Detalhes bibliográficos
Main Authors: Petschacher, Barbara, Nidetzky, Bernd
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2315639/
https://ncbi.nlm.nih.gov/pubmed/18346277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2859-7-9
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