Biochemical and genetic defects in the DNA-dependent protein kinase in murine scid lymphocytes.

The scid gene product has been identified as the 460-kDa catalytic subunit of the DNA-dependent protein kinase (DNA-PKcs p460), a member of the phosphatidylinositol 3-kinase family. DNA-PK activity is undetectable in scid cells, but the molecular basis for this defect has not been identified. Here w...

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Vydáno v:	Mol Cell Biol
Hlavní autoři:	Danska, J S, Holland, D P, Mariathasan, S, Williams, K M, Guidos, C J
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Taylor & Francis 1996
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231550/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8816463/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.16.10.5507
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