Cap-binding protein (eukaryotic initiation factor 4E) and 4E-inactivating protein BP-1 independently regulate cap-dependent translation.
Cap-dependent protein synthesis in animal cells is inhibited by heat shock, serum deprivation, metaphase arrest, and infection with certain viruses such as adenovirus (Ad). At a mechanistic level, translation of capped mRNAs is inhibited by dephosphorylation of eukaryotic initiation factor 4E (eIF-4...
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| 发表在: | Mol Cell Biol |
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| Principais autores: | , |
| 格式: | Artigo |
| 语言: | Inglês |
| 出版: |
Taylor & Francis
1996
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| 主题: | |
| 在线阅读: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231545/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8816458/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.16.10.5450 |
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