The GTPase-activating protein n-chimaerin cooperates with Rac1 and Cdc42Hs to induce the formation of lamellipodia and filopodia.

n-Chimaerin is a GTPase-activating protein (GAP) mainly for Rac1 and less so for Cdc42Hs in vitro. The GAP activity of n-chimaerin is regulated by phospholipids and phorbol esters. Microinjection of Rac1 and Cdc42Hs into mammalian cells induces formation of the actin-based structures lamellipodia an...

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I whakaputaina i:	Mol Cell Biol
Ngā kaituhi matua:	Kozma, R, Ahmed, S, Best, A, Lim, L
Hōputu:	Artigo
Reo:	Inglês
I whakaputaina:	Taylor & Francis 1996
Ngā marau:	Research Article
Urunga tuihono:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231508/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8756665/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.16.9.5069
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