Mutational analysis of Lck in CD45-negative T cells: dominant role of tyrosine 394 phosphorylation in kinase activity.

The CD45 tyrosine phosphatase has been reported to activate the src family tyrosine kinases Lck and Fyn by dephosphorylating regulatory COOH-terminal tyrosine residues 505 and 528, respectively. However, recent studies with CD45- T-cell lines have found that despite the fact that Lck and Fyn were co...

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Pubblicato in:	Mol Cell Biol
Autori principali:	D'Oro, U, Sakaguchi, K, Appella, E, Ashwell, J D
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Taylor & Francis 1996
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231501/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8756658/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.16.9.4996
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