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Creation and characterization of temperature-sensitive mutants of the lck tyrosine protein kinase.

Temperature-sensitive mutants of the lck tyrosine protein kinase were created by the introduction of mutations known to cause temperature sensitivity of the v-src tyrosine protein kinase of Rous sarcoma virus. p56lck activated by mutation of the regulatory site of tyrosine phosphorylation, Tyr-505,...

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Detalhes bibliográficos
Main Authors: Hurley, T R, Amrein, K E, Sefton, B M
Formato: Artigo
Idioma:Inglês
Publicado em: 1992
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC240447/
https://ncbi.nlm.nih.gov/pubmed/1279202
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