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Enhancement of antiproliferative activity of gamma interferon by the specific inhibition of tyrosine dephosphorylation of Stat1.

Gamma interferon (IFN-gamma) signals to the nucleus through the activation, by tyrosine phosphorylation, of the latent cytoplasmic transcription factor Stat1 (signal transducer and activator of transcription). It has been demonstrated that the activity of Stat1 is dependent on tyrosine phosphorylati...

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Publicat a:Mol Cell Biol
Autors principals: Shuai, K, Liao, J, Song, M M
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 1996
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231495/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8756652/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.16.9.4932
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