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An 18-base-pair sequence in the mouse proalpha1(II) collagen gene is sufficient for expression in cartilage and binds nuclear proteins that are selectively expressed in chondrocytes.

The molecular mechanisms by which mesenchymal cells differentiate into chondrocytes are still poorly understood. We have used the gene for a chondrocyte marker, the proalpha1(II) collagen gene (Col2a1), as a model to delineate a minimal sequence needed for chondrocyte expression and identify chondro...

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Publicado no:Mol Cell Biol
Principais autores: Lefebvre, V, Zhou, G, Mukhopadhyay, K, Smith, C N, Zhang, Z, Eberspaecher, H, Zhou, X, Sinha, S, Maity, S N, de Crombrugghe, B
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 1996
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231450/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8754852/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.16.8.4512
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