An 18-base-pair sequence in the mouse proalpha1(II) collagen gene is sufficient for expression in cartilage and binds nuclear proteins that are selectively expressed in chondrocytes.

The molecular mechanisms by which mesenchymal cells differentiate into chondrocytes are still poorly understood. We have used the gene for a chondrocyte marker, the proalpha1(II) collagen gene (Col2a1), as a model to delineate a minimal sequence needed for chondrocyte expression and identify chondro...

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Bibliografiske detaljer

Udgivet i:	Mol Cell Biol
Principais autores:	Lefebvre, V, Zhou, G, Mukhopadhyay, K, Smith, C N, Zhang, Z, Eberspaecher, H, Zhou, X, Sinha, S, Maity, S N, de Crombrugghe, B
Format:	Artigo
Sprog:	Inglês
Udgivet:	Taylor & Francis 1996
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231450/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8754852/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.16.8.4512
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