Distinct regulatory elements control muscle-specific, fiber-type-selective, and axially graded expression of a myosin light-chain gene in transgenic mice.

The fast alkali myosin light chain 1f/3f (MLC1f/3f) gene is developmentally regulated, muscle specific, and preferentially expressed in fast-twitch fibers. A transgene containing an MLC1f promoter plus a downstream enhancer replicates this pattern of expression in transgenic mice. Unexpectedly, this...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Rao, M V, Donoghue, M J, Merlie, J P, Sanes, J R
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 1996
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231388/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8668209/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.16.7.3909
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