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Distinct regulatory elements control muscle-specific, fiber-type-selective, and axially graded expression of a myosin light-chain gene in transgenic mice.

The fast alkali myosin light chain 1f/3f (MLC1f/3f) gene is developmentally regulated, muscle specific, and preferentially expressed in fast-twitch fibers. A transgene containing an MLC1f promoter plus a downstream enhancer replicates this pattern of expression in transgenic mice. Unexpectedly, this...

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Publicat a:Mol Cell Biol
Autors principals: Rao, M V, Donoghue, M J, Merlie, J P, Sanes, J R
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 1996
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Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231388/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8668209/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.16.7.3909
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