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Identification of overlapping DNA-binding and centromere-targeting domains in the human kinetochore protein CENP-C.

The kinetochore in eukaryotes serves as the chromosomal site of attachment for microtubules of the mitotic spindle and directs the movements necessary for proper chromosome segregation. In mammalian cells, the kinetochore is a highly differentiated trilaminar structure situated at the surface of the...

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Publicat a:Mol Cell Biol
Autors principals: Yang, C H, Tomkiel, J, Saitoh, H, Johnson, D H, Earnshaw, W C
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 1996
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231353/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8668174/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.16.7.3576
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