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B-lymphocyte development is regulated by the combined dosage of three basic helix-loop-helix genes, E2A, E2-2, and HEB.

B-lymphocyte development requires the basic helix-loop-helix proteins encoded by the E2A gene. In this study, the control mechanism of E2A was further explored by disruption of the E2A-related genes, E2-2 and HEB. In contrast to E2A, E2-2 and HEB are not essential for the establishment of the B-cell...

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Bibliografiska uppgifter
Huvudupphovsmän: Zhuang, Y, Cheng, P, Weintraub, H
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1996
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC231283/
https://ncbi.nlm.nih.gov/pubmed/8649400
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