Inhibition of cell proliferation by the Mad1 transcriptional repressor.

Mad1 is a basic helix-loop-helix-leucine zipper protein that is induced upon differentiation of a number of distinct cell types. Mad1 dimerizes with Max and recognizes the same DNA sequences as do Myc:Max dimers. However, Mad1 and Myc appear to have opposing functions. Myc:Max heterodimers activate...

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Bibliographic Details
Main Authors: Roussel, M F, Ashmun, R A, Sherr, C J, Eisenman, R N, Ayer, D E
Format: Artigo
Language:Inglês
Published: 1996
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC231271/
https://ncbi.nlm.nih.gov/pubmed/8649388
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