Studies of partially transforming polyomavirus mutants establish a role for phosphatidylinositol 3-kinase in activation of pp70 S6 kinase.

Infection of mouse fibroblasts by wild-type polyomavirus results in increased phosphorylation of ribosomal protein S6 (D.A. Talmage, J. Blenis, and T.L. Benjamin, Mol. Cell. Biol. 8:2309-2315, 1988). Here we identify pp70 S6 kinase (pp70S6K) as a target for signal transduction events leading from po...

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Veröffentlicht in:	Mol Cell Biol
Hauptverfasser:	Dahl, J, Freund, R, Blenis, J, Benjamin, T L
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Taylor & Francis 1996
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231263/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8649380/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.16.6.2728
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