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X-ray structure of the AAC(6′)-Ii antibiotic resistance enzyme at 1.8 Å resolution; examination of oligomeric arrangements in GNAT superfamily members

The rise of antibiotic resistance as a public health concern has led to increased interest in studying the ways in which bacteria avoid the effects of antibiotics. Enzymatic inactivation by several families of enzymes has been observed to be the predominant mechanism of resistance to aminoglycoside...

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Detalhes bibliográficos
Main Authors: Burk, David L., Ghuman, Navleen, Wybenga-Groot, Leanne E., Berghuis, Albert M.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2312454/
https://ncbi.nlm.nih.gov/pubmed/12592013
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