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Cyclin D1 triggers autonomous growth of breast cancer cells by governing cell cycle exit.

Cyclin D1 controls G1-associated processes, including G0-to-G1 and G1-to-S transitions. This study demonstrates a novel aspect of cyclin D1 as a regulator of the transition between G1 and G0. Overexpression of cyclin D1 in MCF7 breast tumor cells resulted in a continued proliferation under low-serum...

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Publicat a:Mol Cell Biol
Autors principals: Zwijsen, R M, Klompmaker, R, Wientjens, E B, Kristel, P M, van der Burg, B, Michalides, R J
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 1996
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231245/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8649362/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.16.6.2554
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