Cyclin D1 triggers autonomous growth of breast cancer cells by governing cell cycle exit.
Cyclin D1 controls G1-associated processes, including G0-to-G1 and G1-to-S transitions. This study demonstrates a novel aspect of cyclin D1 as a regulator of the transition between G1 and G0. Overexpression of cyclin D1 in MCF7 breast tumor cells resulted in a continued proliferation under low-serum...
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| Publicado no: | Mol Cell Biol |
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| Principais autores: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
1996
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231245/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8649362/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.16.6.2554 |
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