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Protein folding coupled to DNA binding in the catalytic domain of bacteriophage λ integrase detected by mass spectrometry

Bacteriophage λ integrase (λ-Int) is the prototypical member of a large family of enzymes that catalyze site-specific DNA recombination via single-strand cleavage and the formation of a Holliday junction intermediate. Crystallographic and biochemical evidence indicate that substantial conformational...

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Detalhes bibliográficos
Main Authors: Kamadurai, Hari B., Subramaniam, Srisunder, Jones, R. Benjamin, Green-Church, Kari B., Foster, Mark P.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2003
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2312437/
https://ncbi.nlm.nih.gov/pubmed/12592032
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