Disrupted Membrane Homeostasis and Accumulation of Ubiquitinated Proteins in a Mouse Model of Infantile Neuroaxonal Dystrophy Caused by PLA2G6 Mutations

Mutations in the PLA2G6 gene, which encodes group VIA calcium-independent phospholipase A2 (iPLA(2)β), were recently identified in patients with infantile neuroaxonal dystrophy (INAD) and neurodegeneration with brain iron accumulation. A pathological hallmark of these childhood neurodegenerative dis...

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Xehetasun bibliografikoak
Egile Nagusiak: Malik, Ibrahim, Turk, John, Mancuso, David J., Montier, Laura, Wohltmann, Mary, Wozniak, David F., Schmidt, Robert E., Gross, Richard W., Kotzbauer, Paul T.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Investigative Pathology 2008
Gaiak:
Regular Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2312364/
https://ncbi.nlm.nih.gov/pubmed/18202189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2008.070823
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