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2-Methoxyestradiol Inhibits Hypoxia-Inducible Factor-1α and Suppresses Growth of Lesions in a Mouse Model of Endometriosis

Endometriosis, the presence of ectopic endometrial tissue outside the uterine cavity, is a common disease affecting women during their reproductive years. Current therapeutic success is often unsatisfactory because of limited insight into disease mechanisms. Nevertheless, angiogenesis plays an essen...

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Detalhes bibliográficos
Main Authors: Becker, Christian M., Rohwer, Nadine, Funakoshi, Tae, Cramer, Thorsten, Bernhardt, Wanja, Birsner, Amy, Folkman, Judah, D’Amato, Robert J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2312351/
https://ncbi.nlm.nih.gov/pubmed/18202195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2008.061244
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