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HIV-1 accessory proteins VPR and Vif modulate antiviral response by targeting IRF-3 for degradation
The activation of IRF-3 during the early stages of viral infection is critical for the initiation of the antiviral response; however the activation of IRF-3 in HIV-1 infected cells has not yet been characterized. We demonstrate that the early steps of HIV-1 infection do not lead to the activation an...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2007
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2312338/ https://ncbi.nlm.nih.gov/pubmed/18082865 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2007.10.042 |
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