Altered cell cycle kinetics, gene expression, and G1 restriction point regulation in Rb-deficient fibroblasts.

Fibroblasts prepared from retinoblastoma (Rb) gene-negative mouse embryos exhibit a shorter G1 phase of the growth cycle and smaller size than wild-type cells. In addition, the mutant cells are no longer inhibited by low levels of cycloheximide at any point in G1 but do remain sensitive to serum wit...

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Detalles Bibliográficos

Publicado en:	Mol Cell Biol
Autores principales:	Herrera, R E, Sah, V P, Williams, B O, Mäkelä, T P, Weinberg, R A, Jacks, T
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Taylor & Francis 1996
Materias:	Research Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231229/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8628308/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.16.5.2402
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