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Altered cell cycle kinetics, gene expression, and G1 restriction point regulation in Rb-deficient fibroblasts.

Fibroblasts prepared from retinoblastoma (Rb) gene-negative mouse embryos exhibit a shorter G1 phase of the growth cycle and smaller size than wild-type cells. In addition, the mutant cells are no longer inhibited by low levels of cycloheximide at any point in G1 but do remain sensitive to serum wit...

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Bibliografiska uppgifter
Huvudupphovsmän: Herrera, R E, Sah, V P, Williams, B O, Mäkelä, T P, Weinberg, R A, Jacks, T
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1996
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC231229/
https://ncbi.nlm.nih.gov/pubmed/8628308
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